Indonesian Journal of Primatology 2024-03-21T14:48:18+07:00 Dr Puji Rianti Open Journal Systems <p>Indonesian Journal of Primatology (InaJP) is an international peer-reviewed and open-access journal that publishes significant and important research from all areas of primatology fields such as biomedical, biology, and conservation. Bio-anthropology, bio-psychology, social, policy, and environmental aspects of primatology are covered by InaJP. <a href="" target="_blank" rel="noopener">E-ISSN 2964-5441</a></p> <p>InaJP is published by Primate Research Center, IPB University, Indonesia. We accept submissions from all over the world. Our Editorial Board members are prominent and active international researchers in primatology fields who ensure an efficient, fair, and constructive peer-review process. All accepted articles will be published on payment of an article-processing charge and will be freely available to all readers with worldwide visibility and coverage.</p> <p><strong>For a limited time, no payment will be charged for articles submitted until 2024.</strong></p> Mosquito Community in Primate Captivity (Tarsius sp.) and its Potential as Transmitters of Zoonotic Mosquito-Borne Diseases. 2023-12-29T20:14:37+07:00 Sarasvathi Cécile Upik Kesumawati Hadi Uus Saepuloh Sela Septima Mariya Huda Shalahudin Darusman <p><span lang="EN-US">By means of conservation, ectoparasites monitoring and surveillance especially mosquitoes in primate captivity become important. Mosquito is one of the ectoparasites which acts as a vector of various types of zoonotic diseases such as Dengue, Zika, Japanese encephalitis, Rift Valley fever, filariasis, and others. This </span><span lang="EN-GB">study was</span><span lang="EN-US"> aimed</span><span lang="EN-GB"> to determine the diversity of mosquito species</span><span lang="EN-US">, </span><span lang="EN-GB">their fluctuations as well as the potential of mosquitoes as a Dengue virus (DENV) </span><span lang="EN-US">vector </span><span lang="EN-GB">around the tarsier </span><span lang="EN-US">captivity</span><span lang="EN-GB"> in the </span><span lang="EN-US">animal </span><span lang="EN-GB">conservation laboratory </span><span lang="EN-GB">IPB Primate Research Center (IPB PRC). </span><span lang="EN-US">M</span><span lang="EN-GB">osquitoes </span><span lang="EN-US">were collected</span><span lang="EN-GB"> from February</span><span lang="EN-US"> to </span><span lang="EN-GB">April 2020 using light traps and sweep net every two hours from </span><span lang="EN-US">06.00 pm to 06.00 am</span><span lang="EN-GB">. Detection of the presence of Dengue virus (DENV) is carried out using Reverse Transcriptase Real-time Polymerase Chain Reaction (RT-qPCR) against Aedes albopictus and Armigeres subalbatus. The results showed that there were 4 </span><span lang="EN-US">species </span><span lang="EN-GB">of mosquitoes caught around the tarsier</span><span lang="EN-US"> captivity</span><span lang="EN-GB"> namely Aedes albopictus, Culex quinquefasciatus, Armigeres subalbatus, and Armigeres foliatus. The dominant mosquito species were Armigeres subalbatus (62.11%) and Aedes albopictus (41.61%). Detection of </span><span lang="EN-US">D</span><span lang="EN-GB">engue virus (DENV) serotypes 1, 2, 3, 4 in Aedes albopictus and Armigeres subalbatus gave negative results.</span><span lang="EN-US"> The presence of mosquitoes that have the potential to carry zoonotic disease around the tarsier captivity in </span><span lang="EN-US">IPB PRC shows the potential for Mosquito-Borne Diseases to both tarsiers and human.</span></p> 2023-12-29T12:50:25+07:00 Copyright (c) 2023 Indonesian Journal of Primatology Morphometric Analysis of Growth in Captive-bred Pig-tailed macaque (Macaca nemestrina Linnaeus 1766) 2024-01-08T11:42:59+07:00 Suryo Saputro Adinda Darayani Azhar Wahyu Putriyani Vinka Aftinata Kusumaputri Suzy Tomongo Amelia Diyan Safitri Permanawati <p><strong>ABSTRACT</strong></p> <p>The pig-tailed macaque has a high vulnerability to human infectious disease pathogens as well as nonhuman primate viruses, making it a good animal model for biomedical research. The goals of this research are to better understand the morphometric and growth rate variations between male and female pig-tailed macaques living in tropical captivity as their natural climate, which will be useful in developing research techniques as well as modifying and developing equipment and instruments.</p> <p>The research was carried out on captive pig-tailed macaques born and kept at the Research Animal Facility in Lodaya (RAF-L) Primate Research Center IPB University (PRC-IPB). The characteristics were separated into four categories: head size, torso, upper limb, and lower limb. During the study period, 70 animals were measured, 32 males and 38 females. The repetition of measurements at distinct timepoints according to body development varies for each individual depending on the animal's situation at that time.</p> <p>There was no visible difference in body and extremity sizes between male and female animals between the ages of 1 and 4 years. Males' head proportions appear to expand consistently in height and width after they are beyond 2 years old, in contrast to females. The growth trend of females tends to decrease from one year of age until sexual maturity, in contrast to males which show a growth spurt at the ages of 1 and 4 years. Differences in size and growth rate indicating sexual dimorphism are visible after the female reaches sexual maturity.</p> <p>&nbsp;</p> 2024-01-07T18:15:37+07:00 Copyright (c) 2024 Indonesian Journal of Primatology The PCNA GENE EXPRESSION AS A MARKER OF ALZHEIMER'S DISEASE IN THE BRAIN OF LONG-TAILED MACAQUES (Macaca fascicularis) 2024-03-21T13:43:09+07:00 Lis Rosmanah Aqila Tsabita Ni Wayan Kurniani Karja Huda Shalahudin Darusman <p>Early diagnosis of Alzheimer's is still difficult to do, thus it is important to carry out further research to find biomarkers that can be used to detect early Alzheimer's disease. Proliferating Cell Nuclear Antigen (<em>PCNA</em>) is known as a proliferation marker, which has the potential to detect neurogenesis in the brain. This study aimed to identify <em>PCNA</em> gene expression in the brain as a marker of Alzheimer’s disease in Macaca fascicularis. Macaca fascicularis was used in this study because of their similarities with humans in terms of their behavioral complexity, as well as high cognitive abilities and the formation of a pathological characteristic of Alzheimer's disease in the brain. This study used the brains of 7 monkeys in the hippocampus and cortical regions. Monkeys previously have been divided into old and adult age groups. The detection of <em>PCNA</em> gene expression was done using RT-qPCR method. The results showed the gene expression tended to be higher in the adult group and the hippocampus region, although based on statistical analysis showed no significant differences</p> 2024-01-20T23:20:02+07:00 Copyright (c) 2024 Indonesian Journal of Primatology Gen expression of Bax and Bcl-2 in Cynomolgus monkeys (Macaca fascicularis) as animal model for Papillomavirus study 2024-03-04T09:06:31+07:00 Sela Septima Mariya Bella Fatima Dora Zaelani Uus Saepuloh Silmi Mariya Huda Shalahudin Darusman Isti Kartika Sari Yuliana <p>Cervical cancer is one of the fourth cancers in the world that occurs in women. Papillomavirus infection has been reported as one of the causative agents of cervical cancer. Apoptotic mechanism is one of the signs of cancer. Cynomolgus monkeys have been widely used as animal models in biomedical research because they are similar to humans in terms of genetics, anatomy, and physiology compared to other animals. Previous studies reported that cynomolgus monkeys have undergone spontaneous infection by papillomavirus, but this infection did not show the phenomenon of cervical cancer. This study aimed to evaluate the prediction of papillomavirus-infected cervical cancer through apoptotic mechanisms regulated by <em>Bax</em> and <em>Bcl-2</em> genes. Gene expression was performed in this study using Real-Time PCR technique. The results showed an increase in <em>Bax</em> and <em>Bcl-2</em> gene expression in positive group cynomolgus monkeys with papillomavirus infection. <em>Bcl-2</em> as anti-apoptotic gene expression increased significantly higher than <em>Bax</em> as pro-apoptotic gene. <em>Bax</em> and <em>Bcl-2</em> have potential as biomarkers to predict the phenomenon of cervical cancer in cynomolgus monkeys with papillomavirus infection.</p> 2024-03-04T08:59:14+07:00 Copyright (c) 2024 Indonesian Journal of Primatology Behavior of Sumatran Lorises (Nycticebus coucang) in the Captive, Primate Research Center-IPB University 2024-03-21T14:48:18+07:00 Ramadhan Adirasa Sundara Abdul Harus Mustari Huda Shalahudin Darusman Hana Hana Intishar Sawitri <p class="section" style="line-height: 150%; margin: 0in 2.9pt .0001pt 2.9pt;">Lorises are protected and endangered animals, according to the IUCN and government regulations in permen <br>LHK No. P.106/2018 , because of poaching, habitat fragmentation, and illegal sales that occur. This study aims to determine the suitability of the cages by observing the behavior and use of the cages space by the sumatra lorises in the Primate Research Center- IPB. The method used is Observation of daily behavior using the animal focal method sampling, namely a direct observation method using one individual and an instantaneous point samplingmethod, namely recording all behavior for a certain duration of time, which will produce data on the percentage of animal behavior every 10 minutes. The time resulting from observations of 3 individual lorises was 144 hours. The study results showed locomotion behavior at 46.69%, social behavior at 2.63%, elimination at 1.6%, rest at 25.11%, grooming at 6.16%, foraging at 2.4%, eating at 3.88%, and being alert at 11.53%. Lorises in Primate Research Center use the entire cages space provided to carry out active and inactive activities. The conservation aspect is sufficiently supportive of the housing and feed aspects provided.</p> 2024-03-21T13:19:17+07:00 Copyright (c) 2024 Indonesian Journal of Primatology