Komposisi Kimia dan Aktivitas Kerang Balelo (Conomurex sp.) dalam Menghambat Enzim α-Glukosidase Chemical Composition and Activity of Balelo Mussels (Conomurex sp.) in Inhibiting Enzyme α-Glucosidase
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Accepted
30 December 2022
Published
30 December 2022
Keywords:
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amino acid, antidiabetic, balelo snails, fatty acid, mineral
Abstract
Balelo snails, gastropod class use as traditional medicine of society in Derawan island. Several studied showed that gastropod class potential used in pharmaceutical and nutraceuticals field. This study aims to determine chemical properties and investigate antidiabetic activity of Balelo snails. this study divided in to 3 step amely first, chemical characterization of balelo snails (amino acid, fatty acid, mineral and metal composition. Second, extraction process using methanol, etyl acetat, and n-hexan, and the third, determine anti diabetic activity. The highest essential amino acid of balelo snails was leucine (2.7%) and non essential was glutamic acid (4.22%). Fresh balelo contained 19.20% of fatty acid, 90.60 mg/kg of iron minerals (Fe). Analyze the activity of a- glucosidase inhibition showed that extract balelo snails in methanol, etyl acetate and n hexane did not potential as anti diabetic.
References
American Association of Cereal Chemist. (1994). Apprived methods of the American Association of Cereal Chemist. Ed ke-9, vol. 1.
Association of Official Analytical Chemist. (2005). Official methods of analysis (18 Edn).
Abdullah, A., Nurjanah, Hidayat, T., & Chairunisah, R. (2017). Karakteristik kimiawi dari daging kerang tahu, kerang salju, dan keong macan. Jurnal Teknologi dan Industri Pangan, 28(1), 78-84.
Achadi, E. L. (2007). Gizi dan kesehatan masyarakat. PT Rajagrafindo Persada.
Ahmed, D. B. (2007). Chemistry of natural products steroids. J. Org. Chem, 26(11), 5A-4784.
Andayani, R., Lisawati, Y., & Maimunah. (2008). Penentuan aktivitas antioksidan, kadar fenolat total dan likopen pada buah tomat (Solanum lycopersicum L). Jurnal Sains dan Teknologi Farmasi, 13(1), 1-9.
Asriyana, & Yuliana. (2012). Produktivitas perairan. Penerbit Bumi Aksara.
Bintang, M. (2010). Biokimia teknik penelitian. Erlangga
Departemen Kesehatan Republik Indonesia. (2008). Modul TOT pelayanan kefarmasian di puskesmas.
Edison, T. (2009). Amino acid: Essential for our bodies. http://livewellnaturally.com.
Febriyanti. (2013). Daging nabati rumput laut (Gracilaria sp) sumber protein dan vitamin B12 pada vegetarian. [Skripsi]. Universitas Diponegoro.
Hairullah, & Budianto, N. E. W. (2017)Perbedaan efektivitas acarbose dengan ekstrak etanol kulit terong ungu (Solanum melongena L) terhadap penurunan kadar gula darah tikus putih (Rattus norvegicus) yang diinduksi sukrosa. Jurnal Ilmiah Kedokteran Wijaya Kusuma, 6(2), 14-20.
Hasanah, N. F., Pringgenies, D., & Wulandari, S. Y. (2012). Karakterisasi metabolit sekunder bakteri simbion gastropoda (Conus miles) dengan metode GC-MS sebagai antibakteri multi drug resistant (MDR). Journal of Marine Research, 1(2), 197-202.
Kamiya, T., Miyukigaoka, Shi, T., & Ibaraki (2002). Biological functions and health benefits of amino acids. Food Ingredients. 206.
Khomsan, A. (2004). Peranan pangan dan gizi untuk kualitas hidup. PT Gramedia Widiasarana Indonesia.
Listiyawati, O. (2012). Pengaruh penambahan plasticizer dan asam palmitat terhadap karakter edible film karaginan. [Skripsi]. Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sebelas Maret.
Mcintosh, J. M., & Jones, R. M. (2001). Cone venom–from accidental sting to deliberate injection. Toxicon, 39(01), 1447-1451.
Nurhikma, Mirsa, & Anggraini, D. (2020). Komponen bioaktif dan aktivitas antioksidan kerang balelo (Conomurex sp.). Jurnal Pengolahan Hasil Perikanan Indonesia, 24(1), 12-19.
Pringgenies, D. (2010). Karakteristik senyawa bioaktif bakteri simbion moluska dengan GC-MS. Jurnal Ilmu dan Teknologi Kelautan Tropis, 2(2), 34-40.
Sancheti, S., & Seo, S. Y. (2009). Chaenomeles sinensis: A Potent α-and β-glucosidase Inhibitor. American Journal of Pharmacology and Toxicology, 4(1), 8-11.
Supariasa, N. D., Bakri, B., & Fajar, I. (2012). Penilaian status gizi. Buku Kedokteran EGC.
Suwandi, R., Nurjanah, & Winem, M. (2014). Proporsi bagian tubuh dan kadar proksimat ikan gabus pada berbagai ukuran. Jurnal Pengolahan Hasil Perikanan Indonesia, 17(1), 22-18.
Tedi, A. K., Warsidah., & Dwi, I. P. (2020). Komponen bioaktif dan aktivitas antioksidan ekstrak kasar kerang ale-ale (Metetrix sp.). Jurnal Laut Khatulistiwa, 3(1), 9-13.
Uju, Nurhayati, T., Ibrahim, B., Trilaksani, W., & Siburian, M. (2009). Karakterisasi dan recovery protein dari air cucian minced fish dengan membran reverse osmosis. Jurnal Pengolahan Hasil Perikanan Indonesia, 12, 115-127.
Villanueva, R., Riba, J., Ruiz-Capillas, C., Gonzales, A. V., & Baeta, M. (2004). Amino acid composition of early stages of cephalopods and effect of amino acid dietary treatments on Octopus vulgaris paralarvae. Aqualculture, 242, 455-478.
Association of Official Analytical Chemist. (2005). Official methods of analysis (18 Edn).
Abdullah, A., Nurjanah, Hidayat, T., & Chairunisah, R. (2017). Karakteristik kimiawi dari daging kerang tahu, kerang salju, dan keong macan. Jurnal Teknologi dan Industri Pangan, 28(1), 78-84.
Achadi, E. L. (2007). Gizi dan kesehatan masyarakat. PT Rajagrafindo Persada.
Ahmed, D. B. (2007). Chemistry of natural products steroids. J. Org. Chem, 26(11), 5A-4784.
Andayani, R., Lisawati, Y., & Maimunah. (2008). Penentuan aktivitas antioksidan, kadar fenolat total dan likopen pada buah tomat (Solanum lycopersicum L). Jurnal Sains dan Teknologi Farmasi, 13(1), 1-9.
Asriyana, & Yuliana. (2012). Produktivitas perairan. Penerbit Bumi Aksara.
Bintang, M. (2010). Biokimia teknik penelitian. Erlangga
Departemen Kesehatan Republik Indonesia. (2008). Modul TOT pelayanan kefarmasian di puskesmas.
Edison, T. (2009). Amino acid: Essential for our bodies. http://livewellnaturally.com.
Febriyanti. (2013). Daging nabati rumput laut (Gracilaria sp) sumber protein dan vitamin B12 pada vegetarian. [Skripsi]. Universitas Diponegoro.
Hairullah, & Budianto, N. E. W. (2017)Perbedaan efektivitas acarbose dengan ekstrak etanol kulit terong ungu (Solanum melongena L) terhadap penurunan kadar gula darah tikus putih (Rattus norvegicus) yang diinduksi sukrosa. Jurnal Ilmiah Kedokteran Wijaya Kusuma, 6(2), 14-20.
Hasanah, N. F., Pringgenies, D., & Wulandari, S. Y. (2012). Karakterisasi metabolit sekunder bakteri simbion gastropoda (Conus miles) dengan metode GC-MS sebagai antibakteri multi drug resistant (MDR). Journal of Marine Research, 1(2), 197-202.
Kamiya, T., Miyukigaoka, Shi, T., & Ibaraki (2002). Biological functions and health benefits of amino acids. Food Ingredients. 206.
Khomsan, A. (2004). Peranan pangan dan gizi untuk kualitas hidup. PT Gramedia Widiasarana Indonesia.
Listiyawati, O. (2012). Pengaruh penambahan plasticizer dan asam palmitat terhadap karakter edible film karaginan. [Skripsi]. Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sebelas Maret.
Mcintosh, J. M., & Jones, R. M. (2001). Cone venom–from accidental sting to deliberate injection. Toxicon, 39(01), 1447-1451.
Nurhikma, Mirsa, & Anggraini, D. (2020). Komponen bioaktif dan aktivitas antioksidan kerang balelo (Conomurex sp.). Jurnal Pengolahan Hasil Perikanan Indonesia, 24(1), 12-19.
Pringgenies, D. (2010). Karakteristik senyawa bioaktif bakteri simbion moluska dengan GC-MS. Jurnal Ilmu dan Teknologi Kelautan Tropis, 2(2), 34-40.
Sancheti, S., & Seo, S. Y. (2009). Chaenomeles sinensis: A Potent α-and β-glucosidase Inhibitor. American Journal of Pharmacology and Toxicology, 4(1), 8-11.
Supariasa, N. D., Bakri, B., & Fajar, I. (2012). Penilaian status gizi. Buku Kedokteran EGC.
Suwandi, R., Nurjanah, & Winem, M. (2014). Proporsi bagian tubuh dan kadar proksimat ikan gabus pada berbagai ukuran. Jurnal Pengolahan Hasil Perikanan Indonesia, 17(1), 22-18.
Tedi, A. K., Warsidah., & Dwi, I. P. (2020). Komponen bioaktif dan aktivitas antioksidan ekstrak kasar kerang ale-ale (Metetrix sp.). Jurnal Laut Khatulistiwa, 3(1), 9-13.
Uju, Nurhayati, T., Ibrahim, B., Trilaksani, W., & Siburian, M. (2009). Karakterisasi dan recovery protein dari air cucian minced fish dengan membran reverse osmosis. Jurnal Pengolahan Hasil Perikanan Indonesia, 12, 115-127.
Villanueva, R., Riba, J., Ruiz-Capillas, C., Gonzales, A. V., & Baeta, M. (2004). Amino acid composition of early stages of cephalopods and effect of amino acid dietary treatments on Octopus vulgaris paralarvae. Aqualculture, 242, 455-478.
Authors
NurhikmaN., RivianiR., WulandariD. A., & MirsaM. (2022). Komposisi Kimia dan Aktivitas Kerang Balelo (Conomurex sp.) dalam Menghambat Enzim α-Glukosidase : Chemical Composition and Activity of Balelo Mussels (Conomurex sp.) in Inhibiting Enzyme α-Glucosidase. Jurnal Pengolahan Hasil Perikanan Indonesia, 25(3), 504-511. https://doi.org/10.17844/jphpi.v25i3.39931
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