Komponen Bioaktif dan Aktivitas Antioksidan Kerang Balelo (Conomurex sp.)

Bioactive Compound and Antioxidant Activity of Balelo Sea Snail (Conomurex sp.)

  • Nurhikma Departemen Teknologi Hasil Perairan, Universitas Borneo Tarakan, Kalimantan Utara
  • Mirsa Departemen Teknologi Hasil Perairan, Universitas Borneo Tarakan, Kalimantan Utara
  • Diah Anggraini Wulandari Research Centre for Oceanografi LIPI http://orcid.org/0000-0002-6873-3804
Keywords: balelo sea snail, bioactive compound, chemical composition, molluscs

Abstract

Molluscs have great potential to developed as a new candidate of antioxidant activity in the pharmaceutical and nutraceutical field. This study aims to investigate the bioactive compound and antioxidant activity of balelo sea snail (Conomurex sp.) from Derawan island, East Kalimantan. Extraction of balelo sea snail was carried out using three types of solvents, such as methanol, ethanol, and ethyl acetate. The analysis method consist of yield analysis, chemical composition, bioactive compounds and antioxidant activity using DPPH. Balelo sea snail had 27.30% of protein content, 2.00% of ash, 10.30% of lipid, and 4.11% of carbohydrate. The yield of balelo sea snail meat was 34.7%, and the yield of methanol, ethanol and ethyl acetate extract were 15.33%, 15.16% and 0.89%, respectively. Balelo sea snail contain alkaloid, tannins, saponins, phenol hydroquinone and steroids. And antioxidants activity of extract methanol and ethanol balelo sea snail (IC50) were 1.055, 8 µg/mL and 1,165.9 µg/mL respectively. Balelo sea snail potential as an antioxidant and has bioactive compound that can be develop in the pharmaceutical and nutraceutical field.

Author Biography

Diah Anggraini Wulandari, Research Centre for Oceanografi LIPI
Zoology

References

[AOAC] Association of Official Analytical Chemist. 2005. Official Method of Analysis of the Association of Official Analytical of Chemist. Virginia (US): The Association of Analytical Chemist, Inc.

Ahmad. 2018. Identifikasi Filum Mollusca (Gastropoda) Di Perairan Palipi Soreang Kecamatan Banggae Kabupaten Majene [Skripsi]. Makassar (ID):Universitas Islam Negeri Alauddin

Arnanda AD, Ambariyanto, Ridlo A. 2005. Fluktuasi Kandungan Proksimat Kerang Bulu (Anadara inflate Reeve) di Perairan Pantai Semarang. Jurnal Ilmu kelautan. 10(2): 78-84

Balcáza JL, Blas I, Ruiz-Zarzuela I, Cunningham D, Vendrell D, Múzquiz JL. 2006. The role of probiotics in aquaculture. Veterinary Microbiol., 114(1): 173-186.

Blunt JW, Copp BR, Munro MHG, Northcote PT, Prinsep, MR. 2006. Marine natural products. Natural Product Reports. 23(1):26–78.

Chairunisah R. 2011. Karakteristik asam amino daging kerang tahu (Meretrix meretrix), kerang salju (Pholas dactylus), dan keong macan (Babylonia spirata). [skripsi]. Bogor (ID): Institut Pertanian Bogor.

Chen CYO, Blumberg JB. 2007. Phytochemical composition of nuts. Asia Pacific Journal of Clinical Nutrition 17(1): 329-332.

Defer D, Bourgougnon N, Fleury Y. 2009. Screening for antibacterial and antiviral activities in three bivalve and two gastropod marine molluscs. Journal Aquaculture. 293(1): 1-7.

Dehkharghanian M, Adenier H, Vijayalakshmi MA. 2010. Analytical methods study of flavonoids in aqueous spinach extract using positive electrospray ionization tandem quadrupole mass spectrometry. Food Chemistry. 121(1): 863–870. DOI: 10.1016/j.foodchem.2010.01. 007

Hafiluddin, Nurjanah, Nurhayati T. 2011. Kandungan gizi dan karakterisasi senyawa bioaktif lintah laut (Discodoris sp.). Jurnal Ilmiah Perikanan dan Kelautan. 3(1): 1-6.

Hafiluddin. 2012. Analisa Kandungan Gizi dan Senyawa Bioaktif Keong Bakau (Telescopium telescopium) di sekitar Perairan Bangkalan. Jurnal Rekayasa. 5(2): 116-122.

Hanani E, Mun’im A, Sekarini R. 2005. Identifikasi senyawa antioksidan dalam spons Callyspongia sp. dari Kepulauan Seribu. Majalah Ilmu Kefarmasian, 2(3): 127-133.

Harborne JB. 2006. Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan. Bandung (ID): ITB.

Kaihena M, Vika L, Maria N. 2011. Efektivitas ekstrak etanol daun sirih (Piper Betle L) terhadap mortalitas larva nyamuk Anopheles sp. dan Culex sp. Jurnal Molluca Medica, 45(1): 88 - 105.

Kaija TA, Warsidah, Prayitno DW. 2020. Komponen bioaktif dan aktivitas antioksidan ektrak kasar kerang Alel-Ale (Metetrix sp). Jurnal Laut Khatulistiwa. 3(1): 9-13

Kalsum U, Hafizah I, Aritrina P, Sulastrianah. 2020. Uji Aktivitas Antioksidan Hidrolisat Protein Kerang Pasir (Semele cordiformis) dengan Metode DPPH. Jurnal Kedokteran Halu Oleo. 7(2): 97-107

Malangngia LP, Meiske S, Sangia , Jessy JE, Paendong. 2012. Penentuan kandungan tanin dan uji aktivitas antioksidan ekstrak biji buah alpukat (Persea americana Mill). Jurnal MIPA Universita Samratulangi. 1(1): 5-10

Martin DW, Mayes JA, Granner DK, Rodwell YW. 1991. Biokimia (harper’s review of Biochemistry). Jakarta (ID): Penerbit buku kedokteran Indonesia

Molyneux P. 2004. The Use of the Stable Free Radical Diphenyl Picrylhdrazyl (DPPH) for Estimating Antioxidant Activity, Songklanakarin Journal Science and Technology. 26(2):211- 21

Mukhriani. 2014. Ekstraksi, pemisahan senyawa, dan identifikasi senyawa aktif. Jurnal kesehatan. 7(2): 361-367.

Nurjanah, Abdullah A, Izzati L. 2010. Aktivitas antioksidan dan komponen bioaktif kerang pisau (Solen spp). Jurnal Ilmu Kelautan 16(3):119-124.

Nurjanah, Zulhamsyah dan Kustiyariyah. 2005. Kandungan mineral dan proksimat kerang darah (anadara granosa) yang diambil dari kabupaten boalemo, gorontalo. Jurnal Buletin Teknologi Hasil Perikanan. 8(2): 15-24

Nurulita Y, Haryanto D, Andreanus AS. 2008. Penapisan aktivitas dan senyawa antidiabetes ekstrak air daun dandang gendis (Clinacanthus nutans). Jurnal Nature Indonesia. 10(2): 98-103.

Pigott MG, dan Tucker WB. 1990. Seafood : effects Of Technology on Nutrition. New York (NYC) : Marcel dekker inc. Hlm.362.

Purbasari, D. 2008. Produksi Dan Karakterisasi Hidrolisat Protein Dari Kerang Mas Ngur (Atactodea striata). [Tesis]. Bogor (ID): Institut Pertanian Bogor.

Purwaningsih S. 2012. Aktivitas antioksidan dan komposisi kimia keong matah merah (Cerithidae obtusa). Jurnal Ilmu Kelautan 17(1):39-48.

Purwaningsih, S. 2006. Antiproliferation study of Matah Merah (Cerithidea obtusa). Proceeding International Seminar and Workshop of Marine biodiversity and Their Potential for Developing Bio-pPharmaceutical Industry in Indonesia.. Jakarta, May 17-18th 2006; Jakarta(ID): Research Centre for Marine and Fisheries Product Processing and Biotechnology Hlm. 150-152.

Rahmayani U, Pringgenies D, Djunaedi A. 2013. Uji aktivitas antioksidan ekstrak kasar keong bakau (Telescopium telescopium) dengan pelarut yang berbeda terhadap metode DPPH (diphenyl picril hidrazil). Journal of Marine Research. 2(4): 36-45

Suptijah P, Yanuarizki O, Nurjanah. 2013. Aktivitas antioksidan dan komponen bioaktif kerang simping (Amusium Pleuronectes). Jurnal Pengolahan Hasil Perairan. 16(3): 242-248

Tadesse M, Gulliksen B, Strim MB, Styrvold OB, Haug T. 2008. Screening for antibacterial and antifungal activities in marine benthic invertebrates from northern Norway. Journal of Invertebrate Pathology. 99(1): 286-293

Wardani RS, Mifbakhiddin, Yokorinanti K. 2010. Pengaruh konsentrasi daun tembelekan terhadap kematian larva Aedes aegypti. Jurnal Kesehatan Masyarakat Indonesia. 6 (2): 30-38.

Widyawati PS, Budianta TDW, Kusuma FA, Wijaya EL. 2014. Difference of solvent polarity to phytochemical content and antioxidant activity of Pluchea indicia Less leaves extracts. International Journal of Pharmacology and Phytochemichal Research 6(4):850- 855.

Yu-Lin H, Kuo YH, Lin YL,Chiang W. 2009. Antioxidative effect and active component from leaves of lotus (Nelumbo nucifera). Journal Agricultural and Food Chemistry. 57(15) : 6623-6629. DOI: 10.1021/jf9 00950z

Zhou DY, Zhu BW, Qiao L, Wu HT, Li DM, Yang JF, Murata Y. 2011. In vitro antioxidant activity of enzymatic hydrolysates prepared from abalone (Haliotis discus hannai Ino) viscera. Food and Bioproducts Processing, 90(2):148-154

Published
2021-04-05