@article{MARGAWATI_RAADSMA_MARTOJO_SUBANDRIYO_MULADNO_1, title={Quantitative Trait Loci (QTL) Analysis for Production Traits of Birth Weight and Weight 360 days in Backcross Sheep}, volume={13}, url={https://jurnal.ipb.ac.id/index.php/hayati/article/view/201}, DOI={10.4308/hjb.13.1.31}, abstractNote={<span style="font-family: Arial,Helvetica,Univers,Zurich BT; color: #003399;">Four half-sib families (n = 382) consisting predominantly of ITT x Merino x Merino backcross progeny, including some F2 progeny were used to analyze QTL for two production traits (Birth weight = BW1 and Body weight at 360 days = BW360). The study exploited differences in weight performance between the Merino and ITT sheep. A total of 141 informative microsatellite markers were used in a genome-wide scan covering the 26 autosomal sheep chromosomes. QTL analysis was conducted online using QTL Express. This study reports the effect of QTL for birth weight on Chromosomes 5 (p < 0.05) at 112cM (0cM-128cM). Location of candidate genes for birth weight was predicted at the region of flanking markers MCM527-BMS1247. A QTL for BW360 days existed on Chromosome 18 (p < 0.01) at 104cM (25.0-125cM). Location of candidate genes related to production traits for body weight 360 days was predicted at the segment of flanking markers of CSSM018-TMR1. Only the QTL on Chromosome 18 retained significance (p < 0.01) under experiment-wide significance testing. This QTL region is being examined for candidate genes by investigating to the homologous human chromosomal segments.<br /><br /> Key words: Quantitative trait loci, production traits, birth weight, weigh 360, backcross sheep </span&gt;}, number={1}, journal={HAYATI Journal of Biosciences}, author={MARGAWATIENDANG TRI and RAADSMAHERMAN WILLEM and MARTOJO, HARIMURTI and SUBANDRIYO, SUBANDRIYO and MULADNO, MULADNO}, year={1}, month={1}, pages={31} }