Optimization Extraction of Xylocarpus granatum Stem as Antioxidant and Antiglycation
Xylocarpus granatum is an Indonesian plant that has bioactives content of phenols and high antioxidant activity on it. The aim of this research was to determine the optimum condition maceration for Xylocarpus granatum stem as antioxidant and antiglycation. The optimum conditions of maceration were effected by the extraction variables (concentration, sample/solvent ratio, extraction time) were evaluated using surface response method. The optimum condition was determined from the recovery of the respons. The optimum condition of maceration is predicted to be achieved when the solvent concentration is 52.25%, the extraction time is 15.92 hours, sample/solvent ratio is 1 g/9 ml with the response (yield, total phenol content, flavonoid, inhibition for 2,2’-diphenylpicryl hydrazyl, capacity of 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), and inhibition antiglycation were 12.81%, 1.95 mg of gallic acid/g extract, 62.33 μg quercetin/g extract, 41.11%, 0.71 TEAC, and 112.33%, respectively). Optimization extraction conditions shows that the extraction variables have significant effect on respons so it can reduce the extraction time, economic, and produce high bioactivite constituens.
HAYATI J Biosci article's license is CC-BY-NC. This license lets others distribute, remix, tweak, and build upon author's work, as long as they credit the original creation.
Authors who submit and publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal/publisher non exclusive publishing rights with the work simultaneously licensed under a https://creativecommons.org/
licenses/by-nc/4.0/Attributi on — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- Authors can still use their work commercially
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).