Synthesis and Characterization of Biocomposite BCP/Collagen for Bone Material Scaffold

  • Anjarsari Anjarsari Departemen Fisika, Fakultas Matematika dan Ilmu Pengetahuan Alam Jl. Meranti, Gedung FMIPA. Wing S Lantai 2 Kampus IPB Darmaga Bogor 16680, Telpon. (0251) 8625728
  • Kiagus Dahlan Departemen Fisika, Fakultas Matematika dan Ilmu Pengetahuan Alam Jl. Meranti, Gedung FMIPA. Wing S Lantai 2 Kampus IPB Darmaga Bogor 16680, Telpon. (0251) 8625728
  • Pipih Suptijah Departemen Teknologi Hasil Perairan, Fakultas Perikanan dan Ilmu Kelautan. Jalan Agatis, Gedung FPIK, Kampus IPB Dramaga Bogor 16680, Telepon: (0251) 8622915,
  • Tetty Kemala Departemen Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Gedung Kimia Wing 1 Lantai 3 Jl. Tanjung Kampus IPB Darmaga Bogor 16680, Telepon/Faks: (0251) 8624567
Keywords: Biphasic Calcium Phosphate (BCP), hidroksiapatit, β-Tricalcium phosphate (β-TCP), collagen, bone scaffold

Abstract

Abstract
Biphasic calcium phosphate (BCP) widely used as implants and scaffolds in different orthopedic and dental application. The aim of this study was to determine synthesis and characteristics of biocomposite BCP/collagen as bone scaffold material. BCP/collagen was classified into three groups: 1) BCP/K5 (5% collagen in scaffold), 2) BCP/K10 (10% collagen in scaffold), and 3) BCP/K15 (15% collagen in scaffold). The samples were characterized by Fourier Transform Infrared (FTIR) Spectroscopy, and Scanning Electron Microscope (SEM) techniques. Overall, concentration of collagen was not significantly different to the spectrum. However, FTIR analysis shows the change intensity in bio-composite BCP/collagen. Collagen intensity Higher concentration when collagen concentration in scaffold higher. Morphology analysis of the scaffold showed significant differences in pore formation. BCP/K15 was showed pores formed in scaffold. Synthesis of composite BCP/collagen does not affect the spectrum of functional groups, but affects the formation of pores in the bone scaffold material.

Published
2017-02-06