Indeks Eritrosit Anak Babi (Sus scrofa) yang Diinduksi Sepsis Pascaresusitasi Cairan
Abstract
Penelitian ini bertujuan untuk mengevaluasi indeks eritrosit (jumlah eritrosit, konsentrasi hemoglobin, hematokrit, VER, HER, KHER) pada anak babi (Sus scrofa) setelah diinduksi sepsis dan diresusitasi oleh cairan koloid (modified fluid gelatin 4%) atau kristaloid (ringer asetat malat). Sepuluh ekor anak babi berumur 2-3 bulan dengan berat badan 8-13 kg dibagi menjadi dua kelompok. Induksi sepsis dilakukan dengan injeksi endotoksin Eschericia coli melalui rute intravena hingga terjadi renjatan sepsis. Resusitasi cairan dilakukan pada saat renjatan sepsis terjadi melalui rute intravena. Kelompok pertama menerima resusitasi cairan menggunakan modified fluid gelatin 4% (MFG 4%) dan pada kelompok yang kedua menerima resusitasi cairan menggunakan cairan ringer asetat malat (RAM). Pengambilan sampel darah dilakukan pada saat setelah anestesi, saat sepsis, dan 3 jam setelah resusitasi cairan. Hasil evaluasi nilai indeks eritrosit menunjukkan bahwa hewan mengalami anemia makrositik regeneratif. Kondisi sepsis dan resusitasi cairan koloid (modified fluid gelatin 4%) maupun cairan kristaloid (ringer asetat malat) tidak memberikan pengaruh yang signifikan terhadap nilai indeks eritrosit.Downloads
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